Company
Built by clinicians and engineers
“Keep patients on the fewest number of meds to get the best end results.”
DisEASE is built by a pharmacist and an engineering team, on the premise that the rules a clinician relies on should be verifiable, versioned, and the same every time.
The founders
Three founders. One mission: make complex pharmacotherapy something every clinician can do confidently.
- Clinical Lead
Trevor Karbowski, PharmD
- Ambulatory care pharmacist and academic educator since 2020, with multiple specialty certifications in chronic disease management.
- Repeatedly guided provider panels from bottom-quartile to top-tier EQM rankings.
- Award-winning deprescribing and therapy-optimization work in dialysis populations.
Why I'm building thisI grew up in an under-resourced community and built my career around underserved patients. I have seen firsthand how suboptimal prescribing strains both the patient and the system trying to help. DisEASE is how I drive change at every level, from leadership decisions to the visit that actually changes a life.
- Technical Lead
Kenton San Miguel
- Designed and built the EVIDENCE CHAIN and RAG pipeline that turns raw clinical sources into pharmacist-verified clinical-concept chunks.
- Built the Rules Builder UI that lets pharmacists author and ship rules without an engineering bottleneck.
- Translates clinical insight into engineering reality so the science is not diluted by software constraints.
Why I'm building thisMost of what I do is give clinicians honest information about what AI is: where it works at the point of care, where it does not, and how to tell the difference. The map between trust and caution is the product I care about building.
- Infrastructure Lead
Wade San Miguel
- Architected the Clinical Weights Algorithm that was later integrated into the EVIDENCE CHAIN and Rules Builder UI.
- Architected the AWS cloud platform, cloud security, and CI/CD pipeline that runs DisEASE in production.
- Built infrastructure to HIPAA security standards that keeps clinical data isolated, auditable, and encrypted end-to-end.
Why I'm building thisI engineer secure-by-design clinical platforms grounded in resilience, traceability, and zero-trust security. The goal: clinical and product teams ship fast without compromising data or trust.
Talk to us
Questions about the engine, a partnership, or working here.