Chronic Disease ManagementGuided by Hybrid AI
“Keep patients on the fewest number of meds to get the best end results.”
Pharmacist-verified rules score every recommendation. Dr. EASE, our agentic AI assistant, explains the ranking and answers follow-ups. The AI never invents the verdict.
How DisEASE Works
Every ranking comes from pharmacist-verified rules. Every explanation cites a source. No PHI collected, and the AI never invents the verdict.
Scoring Engine
Scores the workup against the verified rule library. Returns a ranked, explainable drug list.
No AI hallucination. Same inputs, same answer.Dr. EASE
Explains every ranking with cited sources. Retrieves FDA labels and trial data. Drafts a clinical note.
Every claim cited. Never assigns scores.Disease States We Cover
Your chronic disease expert across Type 2 Diabetes, Hypertension, and Heart Failure.
Type 2 Diabetes
Deterministic medication rankings from pharmacist-verified rules, weighted by A1C target, comorbidities, insurance coverage, and current therapy. Grounded in ADA 2026 Standards of Care.
Available NowHypertension
Guideline-based antihypertensive therapy recommendations with blood pressure target management and compelling indication detection. Grounded in AHA/ACC 2025 Hypertension Guideline.
Available NowHeart Failure (Reduced EF)
Four-pillar GDMT optimization for heart failure with reduced ejection fraction. Grounded in AHA 2022 HF Guideline.
Available NowHeart Failure (Preserved EF)
Comorbidity-driven therapy for heart failure with preserved ejection fraction. Initial release uses HFrEF clinical logic as a placeholder while HFpEF-specific rules are authored. Grounded in AHA 2022 HF Guideline.
Available NowWhy Choose DisEASE
Designed by clinicians, for clinicians. We explore patient-specific factors, pharmacologic barriers, and current plans to develop evidence-based recommendations.
Scored Recommendations
Deny / Caution / Boost engine ranks pharmacotherapy options by clinical fit, insurance coverage, and patient-specific factors.
Compliance Barrier Detection
Identifies RX drug costs, high prior authorization denial risk, and uninsured status before you prescribe.
Safety Screening
Clinical safety layer screens for contraindications, allergies, drug interactions, and flags potentially unsafe prescribing.
Dr. EASE AI Agent
Your agentic AI clinical assistant. Ask questions, request FDA labeling, search clinical trials, or generate documentation. Dr. EASE orchestrates specialized sub-agents to deliver grounded answers.
Dynamic Clinical Notes
Draft SOAP notes in ~15 seconds. Adapted to your writing style and the implemented plan, for clinician review and edit before signing.
Transparent Scoring
Full recommendation trace log so clinicians understand "THE WHY" behind every suggestion. Quality metrics to improve EQM scores.
Frequently Asked Questions
DisEASE is designed to improve EQM scores, a key driver for reimbursement rates. This tool raises the floor for all providers and will postpone costly specialist referrals by giving primary care teams the confidence to manage complex pharmacotherapy.
Yes, workload reduction is always at the forefront. Our dynamic note feature allows a provider to develop an assessment and plan in approximately 15 seconds. Optional EHR integration further streamlines the input process.
Yes. DisEASE is built as HIPAA-compliant software to prevent data breach. We do not store patient-identifying information, and all data transmission is encrypted.
No. DisEASE is stand-alone and fully usable without EHR integration. Optional EHR integration reduces friction at the input step.
Every recommendation ships with a per-rule trace log: which pharmacist-verified rules fired, what evidence they cite, and how they combined into the final ranking. Same inputs always produce the same recommendation. DisEASE is built by practicing clinicians and pharmacists, grounded in current evidence-based guidelines, and continuously improved through provider feedback.
No. Drug rankings come from a deterministic scoring engine verified by clinical pharmacists, so the same patient inputs always produce the same scores. Dr. EASE, our AI assistant, explains the ranking, answers questions, and retrieves FDA labeling or trial data. It cannot rewrite the score or fabricate a recommendation.
DisEASE currently supports Type 2 Diabetes, Hypertension, and Heart Failure (both reduced and preserved ejection fraction).
No. DisEASE is designed for adult patients (18+) and should not be used to guide pediatric treatment. Age-specific pediatric factors are not included in the scoring engine.
Only the clinical data fields provided in the form (age, labs, comorbidities, allergies, current therapies, and other clinical signals). Do not enter personally identifiable information (PII) or protected health information (PHI) such as names or birthdates.
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Built by Clinicians and Engineers
Three founders. One mission: make complex pharmacotherapy something every clinician can do confidently.
Trevor Karbowski, PharmD
- Ambulatory care pharmacist and academic educator since 2020, with multiple specialty certifications in chronic disease management.
- Repeatedly guided provider panels from bottom-quartile to top-tier EQM rankings.
- Award-winning deprescribing and therapy-optimization work in dialysis populations.
I grew up in an under-resourced community and built my career around underserved patients. I have seen firsthand how suboptimal prescribing strains both the patient and the system trying to help. DisEASE is how I drive change at every level, from leadership decisions to the visit that actually changes a life.
Kenton San Miguel
- Designed and built the EVIDENCE CHAIN and RAG pipeline that turns raw clinical sources into pharmacist-verified clinical-concept chunks.
- Built the Rules Builder UI that lets pharmacists author and ship rules without an engineering bottleneck.
- Translates clinical insight into engineering reality so the science is not diluted by software constraints.
Most of what I do is give clinicians honest information about what AI is. Where it works at the point of care, where it does not, and how to tell the difference. The map between trust and caution is the product I care about building.
Wade San Miguel
- Architected the Clinical Weights Algorithm that was later integrated in the EVIDENCE CHAIN and Rules Builder UI.
- Architected the AWS cloud platform, cloud security, and CI/CD pipeline that runs DisEASE in production.
- Built the HIPAA-compliant infrastructure that keeps clinical data isolated, auditable, and encrypted end-to-end.
I engineer secure-by-design clinical platforms grounded in resilience, traceability, and zero-trust security. The goal: clinical and product teams ship fast without compromising data or trust.