Four-pillar GDMT optimization for heart failure with reduced ejection fraction. Grounded in the 2022 AHA/ACC/HFSA HF Guideline.
A deployed, versioned rule set, authored and verified by a pharmacist, scores the workup and returns a ranked list of options with the rules that produced it.
The ranking is deterministic. The same workup returns the same ranked list every time. No part of the score is generated by a language model.
Rules that lower a score are part of the output. Cautions and outright denials arrive with the labs, vitals, allergies and current medications that triggered them, not just the options that survived.
Every rule carries its evidence. Each one cites the guideline text or the FDA labeling it came from, and the citation travels with the recommendation.
Dr. EASE explains, and only explains. The AI layer describes the ranking and retrieves labeling and trial data. It cannot change a score or add a recommendation the engine did not produce.
One of the twelve workups published in the August 2026 Clinical Proof Review, scored by the production engine.
Increase Sacubitril-Valsartan (Entresto)Clinical fit score 88, chosen from 52 candidates the engine weighed for Heart Failure (Reduced EF).
Walk through a scored case first, or create an account and run your own.